Add to ORKGThe monoclonal antibodies HML-1, B-ly7 and Ber-ACT8 recognize intramucosal gut T lymphocytes, activated cells, and hairy cell leukemia. The antigen on hairy cells consists of three glycoproteins (160kD, 130kD and 105kD unreduced; 145kD and 120kD reduced). These peptides have biochemical features reminiscent of integrins but we have shown by immunoprecipitation that they are not known integrin subunits. We have used a newly produced antibody (BP6) to purify this molecule and shown by N-terminal sequence analysis that the smallest subunit is the product of integrin beta-7 cDNA. This molecule is thus a new member of the integrin family of leucoyte adhesion proteins. Immunoprecipitation experiments indicate that the two larger subunits are reco...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
The Hector Battifora mesothelial epitope-1 (HBME-1) monoclonal antibody has been generated against h...
Integrins are heterodimeric cell surface proteins that mediate both cell-cell and cell-extracellular...
The monoclonal antibodies HML-1, B-ly7 and Ber-ACT8 recognize intramucosal gut T lymphocytes, activa...
AbstractWe recently cloned the newest human integrin β subunit, termed β7, from a cDNA library const...
The integrins are a large family of heterodimeric cell-surface glycoproteins that play key roles in ...
The expression of the gut intra-epithelial T-cell associated molecule HML-1, a trimeric protein of 1...
Major histocompatibility complex antigens (MHC antigens) are heterodimeric glycoprotein expressed on...
A molecule defining a subset of patients with hairy cell leukemia (HCL) on the basis of being abunda...
The integrin family of adhesion receptors consists of several heterodimeric glycoproteins, each comp...
Recent immunophenotypic analysis has shown that the heterogeneous expression of the adhesion molecul...
Spleen cells from a Balb/c mouse immunized with a human myeloma line ARH-77 were fused with cells of...
The LIP-6 MAb was produced against the undifferentiated cell line bh2-1 and recognizes an antigen ex...
Monoclonal antibodies reactive with hairy cell leukemia were developed to aid in the diagnosis of th...
This report describes the characterization and expressIon of a human myelold differen. tiation antig...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
The Hector Battifora mesothelial epitope-1 (HBME-1) monoclonal antibody has been generated against h...
Integrins are heterodimeric cell surface proteins that mediate both cell-cell and cell-extracellular...
The monoclonal antibodies HML-1, B-ly7 and Ber-ACT8 recognize intramucosal gut T lymphocytes, activa...
AbstractWe recently cloned the newest human integrin β subunit, termed β7, from a cDNA library const...
The integrins are a large family of heterodimeric cell-surface glycoproteins that play key roles in ...
The expression of the gut intra-epithelial T-cell associated molecule HML-1, a trimeric protein of 1...
Major histocompatibility complex antigens (MHC antigens) are heterodimeric glycoprotein expressed on...
A molecule defining a subset of patients with hairy cell leukemia (HCL) on the basis of being abunda...
The integrin family of adhesion receptors consists of several heterodimeric glycoproteins, each comp...
Recent immunophenotypic analysis has shown that the heterogeneous expression of the adhesion molecul...
Spleen cells from a Balb/c mouse immunized with a human myeloma line ARH-77 were fused with cells of...
The LIP-6 MAb was produced against the undifferentiated cell line bh2-1 and recognizes an antigen ex...
Monoclonal antibodies reactive with hairy cell leukemia were developed to aid in the diagnosis of th...
This report describes the characterization and expressIon of a human myelold differen. tiation antig...
The major histocompatibility complex (MHC) class II antigens were originally described to be express...
The Hector Battifora mesothelial epitope-1 (HBME-1) monoclonal antibody has been generated against h...
Integrins are heterodimeric cell surface proteins that mediate both cell-cell and cell-extracellular...