The synthesis of a new class of auxiliary based chiral synthons, gamma-alkoxy-2(5H)-furanones, is described. The multifunctional compounds enter a variety of asymmetric transformations leading to acyclic- and cyclic-products with up to four new stereogenic centers in a single operation with stereoselectivities exceeding 98%. Applications in new routes to an enantiomerically pure beta-lactam and lignans are given
gamma-Butenolides, gamma-butyrolactones, and derivatives, especially in enantiomerically pure form, ...
[[abstract]]The first examples of highly diastereoselective and asymmetric Diets-Alder cycloaddition...
Based on the asymmetric Michael addition to 5(R)- and 5(S)-menthyloxy-2[5H]-furanone two new synthes...
The synthesis of a new class of auxiliary based chiral synthons, γ-alkoxy-2(5H)-furanones, is descri...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
Based on the asymmetric Michael addition to 5(R)- and 5(S)-menthyloxy-2[5H]-furanone two new synthes...
The enantioselective synthesis of a N-benzyl substituted beta-lactam 5a, a precursor for carbapenem ...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
A new strategy for general asymmetric synthesis of chiral butenolides 7a-h is established by utilizi...
The synthesis of enantiomerically pure β-amino-γ-butyrolactones via asymmetric conjugate addition of...
A chemoenzymatic method is described for the asymmetric synthesis of benzylbutyrolactones. (R)-5-Ace...
gamma-Butenolides, gamma-butyrolactones, and derivatives, especially in enantiomerically pure form, ...
[[abstract]]The first examples of highly diastereoselective and asymmetric Diets-Alder cycloaddition...
Based on the asymmetric Michael addition to 5(R)- and 5(S)-menthyloxy-2[5H]-furanone two new synthes...
The synthesis of a new class of auxiliary based chiral synthons, γ-alkoxy-2(5H)-furanones, is descri...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
Based on the asymmetric Michael addition to 5(R)- and 5(S)-menthyloxy-2[5H]-furanone two new synthes...
The enantioselective synthesis of a N-benzyl substituted beta-lactam 5a, a precursor for carbapenem ...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
A new strategy for general asymmetric synthesis of chiral butenolides 7a-h is established by utilizi...
The synthesis of enantiomerically pure β-amino-γ-butyrolactones via asymmetric conjugate addition of...
A chemoenzymatic method is described for the asymmetric synthesis of benzylbutyrolactones. (R)-5-Ace...
gamma-Butenolides, gamma-butyrolactones, and derivatives, especially in enantiomerically pure form, ...
[[abstract]]The first examples of highly diastereoselective and asymmetric Diets-Alder cycloaddition...
Based on the asymmetric Michael addition to 5(R)- and 5(S)-menthyloxy-2[5H]-furanone two new synthes...