Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration often leads to tearing of the annulus fibrosus (AF) and extrusion of the nucleus pulposus (NP), which compresses the nerves. Current treatment involves removing the herniated NP and suturing the damaged AF tissue. This surgical approach has several drawbacks. In this study, we designed a biodegradable AF closure system comprising a tissue engineering scaffold, a supporting membrane and an adhesive material, to not only restore the function of the herniated disc but also to promote tissue regeneration. Materials and Methods: Porous scaffolds with precisely defined architectures were built by stereolithography using resins based on poly(trimeth...
Degeneration of the intervertebral disk is the main cause of chronic back pain. Disk degeneration of...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Degeneration of the intervertebral disk is the main cause of chronic back pain. Disk degeneration of...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Purpose: Intervertebral disk degeneration is the main cause of chronic back pain. Disk degeneration ...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Recurrent intervertebral disc (IVD) herniation and degenerative disc disease have been identified as...
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the an...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Degeneration of the intervertebral disk is the main cause of chronic back pain. Disk degeneration of...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...
Unrepaired defects in the annulus fibrosus of intervertebral disks are associated with degeneration ...