Objectives: The essential role of erythrocytes as oxygen carriers is historically well established, but their function to aggregate and the consequences on the microcirculation is under debate. The pathogenic potential of low erythrocyte aggregation could be important for patients undergoing on-pump cardipopulmonary bypass. These patients are severely hemodiluted due to preoperative isovolemic hemodilution (IHD), circuit priming, and large fluid infusions perioperatively. Considering the vascular endothelium sensitivity to variations in blood rheology, the authors hypothesize that low erythrocyte aggregation will be responsible for activation of vascular endothelium during acute IHD. Methods: Acute IHD (30 mL/kg exchange transfusion with co...
Background: Cardiac surgery with cardiopulmonary bypass (CPB) is commonly associated with acute kidn...
OBJECTIVES: Ischaemia-reperfusion injury is a necessary part of organ transplantation and a key dete...
Introduction: Excessive hemodilution during cardiopulmonary bypass (CPB) is associated with an incre...
Objectives: The essential role of erythrocytes as oxygen carriers is historically well established, ...
Objective: The bio-incompatibility of the cardiopulmonary bypass (CPB) circuit and the use of artifi...
BACKGROUND: Hemodilution is the main Cause of a low hematocrit concentration during cardiopulmonary ...
This thesis evaluates three most important etiological factors for organ injury namely, intravenous ...
Erythrocyte aggregation is known to be affected by a number of factors including the concentration o...
Erythrocyte aggregation is known to be affected by a number of factors including the concentration o...
Extracorporeal membrane oxygenators are used in critical care for the management of severe respirato...
gery, the severity of the inflammatory response is related to the patient outcome. However, determin...
International audienceExtracorporeal membrane oxygenation (ECMO) is an extracorporeal circulation us...
Many investigators advocate aggressive fluid therapy in sepsis, yet changes in the microcirculation...
Purpose: Endothelial cells (EC) secrete vasoactive eicosanoids, which maintain organ blood flow. Bec...
Abstract: BACKGROUND: Abnormal erythrocyte deformability can cause severe complications during cardi...
Background: Cardiac surgery with cardiopulmonary bypass (CPB) is commonly associated with acute kidn...
OBJECTIVES: Ischaemia-reperfusion injury is a necessary part of organ transplantation and a key dete...
Introduction: Excessive hemodilution during cardiopulmonary bypass (CPB) is associated with an incre...
Objectives: The essential role of erythrocytes as oxygen carriers is historically well established, ...
Objective: The bio-incompatibility of the cardiopulmonary bypass (CPB) circuit and the use of artifi...
BACKGROUND: Hemodilution is the main Cause of a low hematocrit concentration during cardiopulmonary ...
This thesis evaluates three most important etiological factors for organ injury namely, intravenous ...
Erythrocyte aggregation is known to be affected by a number of factors including the concentration o...
Erythrocyte aggregation is known to be affected by a number of factors including the concentration o...
Extracorporeal membrane oxygenators are used in critical care for the management of severe respirato...
gery, the severity of the inflammatory response is related to the patient outcome. However, determin...
International audienceExtracorporeal membrane oxygenation (ECMO) is an extracorporeal circulation us...
Many investigators advocate aggressive fluid therapy in sepsis, yet changes in the microcirculation...
Purpose: Endothelial cells (EC) secrete vasoactive eicosanoids, which maintain organ blood flow. Bec...
Abstract: BACKGROUND: Abnormal erythrocyte deformability can cause severe complications during cardi...
Background: Cardiac surgery with cardiopulmonary bypass (CPB) is commonly associated with acute kidn...
OBJECTIVES: Ischaemia-reperfusion injury is a necessary part of organ transplantation and a key dete...
Introduction: Excessive hemodilution during cardiopulmonary bypass (CPB) is associated with an incre...