Add to ORKGExpression of CD27 on malignant plasma cells (PC) (CD138(+) CD38(++) ) was analysed in a cross-sectional study of bone marrow (BM) samples from multiple myeloma (MM) patients (n = 28), monoclonal gammopathy of undetermined significance (MGUS) patients (n = 6) and BM PC from healthy donors (n = 4). MM PC expressed CD27 with a variable, lower intensity pattern compared with the consistent high expression in MGUS and healthy donors. MM patients in complete clinical remission displayed a higher percentage of CD27(+) PC compared with patients at diagnosis, relapse or in partial remission. In MM, loss of CD27 correlated with loss of CD19 (R (2) = 0.4, P <0.0001). Human MM cell lines (n = 9) did not express CD27 whereas de novo plasma cell leukaem...
GEM (Grupo Español de Mieloma)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Mal...
Multiple myeloma (MM) is the most common form of plasma cell dyscrasia, characterized by a marked he...
The immunological bone marrow (BM) microenvironment plays a major role in controlling growth and sur...
Expression of CD27 on malignant plasma cells (PC) (CD138(+) CD38(++) ) was analysed in a cross-secti...
International audienceCD28 expression was thoroughly investigated on plasma cells of monoclonal gamm...
We evaluated the association between the expression of myeloid antigens on neoplastic plasma cells a...
Multiple myeloma (MM) progression is dependent on its interaction with the bone marrow microenvironm...
The notion that plasma cells (PCs) are terminally-differentiated has prevented intensive research in...
textabstractThe notion that plasma cells (PCs) are terminally differentiated has prevented intensive...
Aim. To analyze the relationship between expression of aberrant CD45, CD19, CD56 markers on the plas...
Surface antigens are commonly used in flow cytometry assays for the diagnosis of multiple myeloma (M...
Bone marrow plasma cells (PCs) from 74 patients with newly diagnosed multiple myeloma (MM), 5 with m...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Multiple Myeloma (MM) is the most common form of plasma cell dyscrasia, characterized by a marked he...
Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease p...
GEM (Grupo Español de Mieloma)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Mal...
Multiple myeloma (MM) is the most common form of plasma cell dyscrasia, characterized by a marked he...
The immunological bone marrow (BM) microenvironment plays a major role in controlling growth and sur...
Expression of CD27 on malignant plasma cells (PC) (CD138(+) CD38(++) ) was analysed in a cross-secti...
International audienceCD28 expression was thoroughly investigated on plasma cells of monoclonal gamm...
We evaluated the association between the expression of myeloid antigens on neoplastic plasma cells a...
Multiple myeloma (MM) progression is dependent on its interaction with the bone marrow microenvironm...
The notion that plasma cells (PCs) are terminally-differentiated has prevented intensive research in...
textabstractThe notion that plasma cells (PCs) are terminally differentiated has prevented intensive...
Aim. To analyze the relationship between expression of aberrant CD45, CD19, CD56 markers on the plas...
Surface antigens are commonly used in flow cytometry assays for the diagnosis of multiple myeloma (M...
Bone marrow plasma cells (PCs) from 74 patients with newly diagnosed multiple myeloma (MM), 5 with m...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Multiple Myeloma (MM) is the most common form of plasma cell dyscrasia, characterized by a marked he...
Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease p...
GEM (Grupo Español de Mieloma)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Mal...
Multiple myeloma (MM) is the most common form of plasma cell dyscrasia, characterized by a marked he...
The immunological bone marrow (BM) microenvironment plays a major role in controlling growth and sur...