Add to ORKGWhen bacteria are cultured in medium with multiple carbon substrates, they frequently consume these substrates simultaneously. Building on recent advances in the understanding of metabolic coordination exhibited by Escherichia coli cells through cAMP-Crp signaling, we show that this signaling system responds to the total carbon-uptake flux when substrates are co-utilized and derive a mathematical formula that accurately predicts the resulting growth rate, based only on the growth rates on individual substrates
Background\ud Carbon catabolite repression (CCR) is critical for optimal bacterial growth, and in ba...
Abstract Fitness of bacteria is determined both by how fast cells grow when nutrients are abundant a...
Global control influences the regulation of many individual subsystems by superimposed regulator pro...
When bacteria are cultured in medium with multiple carbon substrates, they frequently consume these ...
When bacteria are cultured in medium with multiple carbon substrates, they frequently consume these ...
peer reviewedIn Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransf...
In Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransferase systems...
In Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransferase systems...
Many microorganisms exhibit nutrient preferences, exemplified by the 'hierarchical' consumption of c...
Bacteria in changing environments must constantly adapt to grow and survive. The adaptive response t...
Mathematical models which utilize standard reaction kinetics to describe microbial growth are genera...
Carbon catabolite repression (CCR) in bacterial cells leads to their selective consumption of a sing...
The microbial growth in multi-substrate environments may be viewed as an optimal resources allocatio...
For many years understanding of the metabolism of Escherichia coli has been one of the main topics i...
Growth of microorganisms on substitutable substrate mixtures display diverse growth dynamics charact...
Background\ud Carbon catabolite repression (CCR) is critical for optimal bacterial growth, and in ba...
Abstract Fitness of bacteria is determined both by how fast cells grow when nutrients are abundant a...
Global control influences the regulation of many individual subsystems by superimposed regulator pro...
When bacteria are cultured in medium with multiple carbon substrates, they frequently consume these ...
When bacteria are cultured in medium with multiple carbon substrates, they frequently consume these ...
peer reviewedIn Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransf...
In Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransferase systems...
In Escherichia coli K-12, components of the phosphoenolpyruvate-dependent phosphotransferase systems...
Many microorganisms exhibit nutrient preferences, exemplified by the 'hierarchical' consumption of c...
Bacteria in changing environments must constantly adapt to grow and survive. The adaptive response t...
Mathematical models which utilize standard reaction kinetics to describe microbial growth are genera...
Carbon catabolite repression (CCR) in bacterial cells leads to their selective consumption of a sing...
The microbial growth in multi-substrate environments may be viewed as an optimal resources allocatio...
For many years understanding of the metabolism of Escherichia coli has been one of the main topics i...
Growth of microorganisms on substitutable substrate mixtures display diverse growth dynamics charact...
Background\ud Carbon catabolite repression (CCR) is critical for optimal bacterial growth, and in ba...
Abstract Fitness of bacteria is determined both by how fast cells grow when nutrients are abundant a...
Global control influences the regulation of many individual subsystems by superimposed regulator pro...