Low-carbon power systems are needed by the year 2050 to meet climate change mitigation targets. This dissertation investigates the operational and economic feasibility of such future low-carbon power systems by simulating the Dutch and European power systems. Particular attention is paid to the impacts of intermittent renewable energy sources (iRES) on the power system, the operational and economic performance of power plants with carbon capture and storage (CCS) and the flexibility of the power system. It is found that iRES affect the operation of power systems, but that their impacts are manageable. Overall, sufficient operational flexibility is available in future low-carbon power systems to accommodate variable electricity production of...