Motion of a massive microsphere bound to a spherical vesicle

We study the motion of a small solid particle (a few micrometers in size) attached to the membrane of a spherical giant lipid vesicle. By means of optical manipulation, the particle is first brought near the top of the vesicle, and released. We determine the friction experienced by the particle moving along the vesicle surface under the action of gravity. From experiments with latex and glass beads, we check that SOPC membranes are fluid at room temperature (static shear modulus u = 0) and estimate the shear viscosity of SOPC bilayers: nm = 3 * 10^(-6) surface poise