Use of different cytometric techniques to study the cytotoxic interaction between human natural killer cells and K562 target cells

The studies described in this manuscript have been aimed to obtain a better insight into the cytotoxic interaction between human Natural Killer (NK) cells and K562 target cells1. In order to obtain information about crucial processes leading to target cell death, the processes taking place in the target cell during a killer cell attack were studied using different optical techniques. Furthermore, flow cytometric methods for determination of the phenotype and the cytotoxic activity of killer cells were developed