Synthesis of neutral, water-soluble calix[4]arenes

Grote gansey, M.H.B.
Grote Gansey, Marcel H.B.
Steemers, Frank J.
Steemers, F.J.
Verboom, Willem
Reinhoudt, David

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Publication date

January 1997

DOI

10.1055/s-1997-4506

ISSN

0039-7881

Citation count (estimate)

Abstract

Novel neutral water-soluble calix[4]arenes were synthesized via chlorosulfonylation of lower rim functionalized calix[4]arenes followed by reaction with hydroxyl group containing amines. The solubility of these calix[4]arenes sulfonamides in water varies from ∼ 10-5 to 3.1⋅10-1 M. A route via hydrophobically protected amines improves the purification

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Synthesis of neutral, water-soluble calix[4]arenes

Abstract

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Synthesis of neutral, water-soluble calix[4]arenes

Abstract

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