Screening of antibacterial drugs from marine gastropod Chicoreus ramosus (Linnaeus, 1758)

Objective: To screen the antibacterial drugs from different solvent extracts of tissue and egg of marine gastropods Chicoreus ramosus against clinically isolated human pathogenic bacteria. Methods: Different solvent extracts of Chicoreus ramosus was screened for their activity against Vibrio parehaemolyticus (J13300), Aeromonus hydrophilla (IDH1585), Salmonella typhi (C6953), Salmonella paratyphi A (C6915), Vibrio cholerae (IDH5439) and Escherichia coli (H10407) using standard well diffusion method and its minimum inhibitory concentration. Results: The study revealed that the acetone and chloroform extract of both the tissues and egg inhibited the growth of the tested pathogenic bacterial strains. The minimum inhibitory concentration of both the extract ranged from 4 to 12 mg/mL. Conclusions: These results suggest that marine gastropods tissue and egg extract contains comparatively good antibacterial activity