The Parathyroid Adenoma

Parathyroid adenomas are benign neoplasms with a predilection for the inferior parathyroid glands. Genetic mutations identified as contributing to development of parathyroid adenomas include MEN 1 and cyclin D1. Predisposing factors include female gender and radiation exposure. The natural history of parathyroid adenomas, including malignant potential, is poorly understood. Specific indications for surgical removal in addition to surgical and non surgical therapeutic modalities are discussed in this review. [Arch Clin Exp Surg 2014; 3(4.000): 240-246