Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents
- Martina Rothenbühler, MSc
- Crochan J O'Sullivan, MD
- Stefan Stortecky, MD
- Giulio G Stefanini, MD
- Ernest Spitzer, MD
- Janne Estill, PhD
- Nikesh R Shrestha, MD
- Olivia Keiser, PhD
- Prof. Peter Jüni, MD
- Dr. Thomas Pilgrim, MD
DOIAbstract
Background: Rheumatic heart disease accounts for up to 250 000 premature deaths every year worldwide and can be regarded as a physical manifestation of poverty and social inequality. We aimed to estimate the prevalence of rheumatic heart disease in endemic countries as assessed by different screening modalities and as a function of age. Methods: We searched Medline, Embase, the Latin American and Caribbean System on Health Sciences Information, African Journals Online, and the Cochrane Database of Systematic Reviews for population-based studies published between Jan 1, 1993, and June 30, 2014, that reported on prevalence of rheumatic heart disease among children and adolescents (≥5 years to <18 years). We assessed prevalence of clinically s...
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