Add to ORKGAcute lymphoblastic leukemia (ALL) in infants (<1 year of age) is characterized by a high incidence (~80%) of rearrangements of the MLL gene, resistance to several important chemotherapeutic drugs, and a poor treatment outcome. With overall survival rates for infant ALL not exceeding 50%, current chemotherapeutic regime
textabstractAcute lymphoblastic leukemia (ALL) in infants (< 1 year) is characterized by a poor prog...
Presence of the MLL gene rearrangement at 11q23 is an important prognostic feature. Moreover, the re...
Although 90% of children with acute lymphoblastic leukemia (ALL) are now cured, the prognosis for in...
The treatment of children diagnosed with acute lymphoblastic leukemia (ALL) has improved significant...
Infant acute lymphoblastic leukemia (ALL) with MLL rearrangements (MLL-R) represents a distinct leuk...
Includes 3 unnumbered pages at the end of the article. Published online 2 March 2015Infant acute lym...
Acute lymphoblastic leukemia (ALL) in infants (< 1 year) is characterized by a poor prognosis and...
Aim. To evaluate the relation between genomic DNA breakpoints in MLL and translocation partner genes...
We and others have recently reported a high frequency (70-80%) of ALL-1 (MLL, HRX, HTRX) gene rearra...
Contemporary treatments have resulted in 5-year event-free survival rates (EFS) of approximately 75%...
Distinct from most other acute lymphoblastic leukemia (ALL), infant ALL with mixed lineage leukemia ...
The successful treatment of paediatric malignancies by multimodal therapy has improved outcomes for ...
AbstractMLL-rearranged acute lymphoblastic leukaemia (ALL) in infants is the most difficult-to-treat...
The aim of this study was to identify immunobiological subgroups in 133 infant acute lymphoblastic l...
Acute lymphoblastic leukemia (ALL) in infants is characterized by rearrange-ments of the mixed linea...
textabstractAcute lymphoblastic leukemia (ALL) in infants (< 1 year) is characterized by a poor prog...
Presence of the MLL gene rearrangement at 11q23 is an important prognostic feature. Moreover, the re...
Although 90% of children with acute lymphoblastic leukemia (ALL) are now cured, the prognosis for in...
The treatment of children diagnosed with acute lymphoblastic leukemia (ALL) has improved significant...
Infant acute lymphoblastic leukemia (ALL) with MLL rearrangements (MLL-R) represents a distinct leuk...
Includes 3 unnumbered pages at the end of the article. Published online 2 March 2015Infant acute lym...
Acute lymphoblastic leukemia (ALL) in infants (< 1 year) is characterized by a poor prognosis and...
Aim. To evaluate the relation between genomic DNA breakpoints in MLL and translocation partner genes...
We and others have recently reported a high frequency (70-80%) of ALL-1 (MLL, HRX, HTRX) gene rearra...
Contemporary treatments have resulted in 5-year event-free survival rates (EFS) of approximately 75%...
Distinct from most other acute lymphoblastic leukemia (ALL), infant ALL with mixed lineage leukemia ...
The successful treatment of paediatric malignancies by multimodal therapy has improved outcomes for ...
AbstractMLL-rearranged acute lymphoblastic leukaemia (ALL) in infants is the most difficult-to-treat...
The aim of this study was to identify immunobiological subgroups in 133 infant acute lymphoblastic l...
Acute lymphoblastic leukemia (ALL) in infants is characterized by rearrange-ments of the mixed linea...
textabstractAcute lymphoblastic leukemia (ALL) in infants (< 1 year) is characterized by a poor prog...
Presence of the MLL gene rearrangement at 11q23 is an important prognostic feature. Moreover, the re...
Although 90% of children with acute lymphoblastic leukemia (ALL) are now cured, the prognosis for in...