Nitroimidazole derivatives such as Metronidazole (MTZ) have been used as anti- protozoa and anti-anaerobic bacteria. In this study several derivatives of MTZ were synthesized and evaluated against Giardia lamblia cyst. MTZ were reacted with several alkyl halide to obtain o-alkyl MTZ derivatives, then products were purified and their chemical structures were confirmed by spectral analysis (1HNMR and Mass). In order to assess biological evaluation, all compounds were investigated against 25 Giardia samples isolated from Giardia-infected patients. Results showed that compound 2 had the most activity on cyst of Giardia in comparison with MTZ
Previous studies in our laboratory have shown that albendazole is effective against Giardia spp. in ...
International audienceThe 5-nitroimidazole (NI) compound C17, with a side chain carrying a remote ph...
Metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum anti...
Nitroimidazole derivatives such as Metronidazole (MTZ) have been used as anti- protozoa and anti-ana...
Giardiasis is a protozoal infection of small intestine caused by giardia lamblia. The disease is usu...
The chemotherapeutic agents used for the treatment of giardiasis are often associated with adverse s...
Giardia lamblia is a protozoa which causes giardiasis, and is a major cause of parasitic diarrheal d...
AbstractThe chemotherapeutic agents used for the treatment of giardiasis are often associated with a...
AbstractDiarrhoeal diseases caused by the intestinal parasites Giardia lamblia and Entamoeba histoly...
Protozoan parasites, such as Giardia lamblia and Trichomonas vaginalis, cause the most prevalent inf...
Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in trop...
27-30Preparation of metronidazole derivatives 2-5 is described and the results of antimicrobial eva...
The activities of 11 5-nitroimidazole compounds have been compared against Giardia intestinalis in v...
Parasitic and bacterial infections affecting the gastrointestinal tract represent a significant caus...
Giardia lamblia is an important and ubiquitous cause of diarrheal disease. The primary agents in the...
Previous studies in our laboratory have shown that albendazole is effective against Giardia spp. in ...
International audienceThe 5-nitroimidazole (NI) compound C17, with a side chain carrying a remote ph...
Metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum anti...
Nitroimidazole derivatives such as Metronidazole (MTZ) have been used as anti- protozoa and anti-ana...
Giardiasis is a protozoal infection of small intestine caused by giardia lamblia. The disease is usu...
The chemotherapeutic agents used for the treatment of giardiasis are often associated with adverse s...
Giardia lamblia is a protozoa which causes giardiasis, and is a major cause of parasitic diarrheal d...
AbstractThe chemotherapeutic agents used for the treatment of giardiasis are often associated with a...
AbstractDiarrhoeal diseases caused by the intestinal parasites Giardia lamblia and Entamoeba histoly...
Protozoan parasites, such as Giardia lamblia and Trichomonas vaginalis, cause the most prevalent inf...
Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in trop...
27-30Preparation of metronidazole derivatives 2-5 is described and the results of antimicrobial eva...
The activities of 11 5-nitroimidazole compounds have been compared against Giardia intestinalis in v...
Parasitic and bacterial infections affecting the gastrointestinal tract represent a significant caus...
Giardia lamblia is an important and ubiquitous cause of diarrheal disease. The primary agents in the...
Previous studies in our laboratory have shown that albendazole is effective against Giardia spp. in ...
International audienceThe 5-nitroimidazole (NI) compound C17, with a side chain carrying a remote ph...
Metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum anti...