Add to ORKGHistone post-translational modification (PTM) antibodies are essential research reagents in chromatin biology. However, they suffer from variable properties and insufficient documentation of quality. Antibody manufacturers and vendors should provide detailed lot-specific documentation of quality, rendering further quality checks by end-customers unnecessary. A shift from polyclonal antibodies towards sustainable reagents like monoclonal or recombinant antibodies or histone binding domains would help to improve the reproducibility of experimental work in this field
Research antibodies are used in a wide range of bioscience disciplines, yet it is common to hear dis...
Antibodies are critical reagents to detect and characterize proteins. It is commonly understood that...
Antibodies specific for histone post-translational modifications (PTMs) have been central to our und...
We have tested the specificity and utility of more than 200 antibodies raised against 57 different h...
Post-translational modifications (PTMs) of histones constitute a major chromatin indexing mechanism,...
Access to high quality antibodies is a necessity for the study of histones and their posttranslation...
We report a general method to examine the recognition of post-translational modifications (PTMs) by ...
We present here the very robust characterization and quality control (QC) process that we have estab...
BackgroundThe robustness of ChIP-seq datasets is highly dependent upon the antibodies used. Currentl...
Antibodies directed against histone posttranslational modifications (PTMs) are critical tools in epi...
In the eukaryotic genome, DNA is organized into nucleosomes, which are comprised by 147bp of DNA wra...
Imagine you’re just starting in a lab. Your new PI decides to test your mettle at the bench with a s...
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure ...
SummaryIncreasing evidence suggests that histone posttranslational modifications (PTMs) function in ...
Problems with antibody quality have been described in numerous recent publications. In the present c...
Research antibodies are used in a wide range of bioscience disciplines, yet it is common to hear dis...
Antibodies are critical reagents to detect and characterize proteins. It is commonly understood that...
Antibodies specific for histone post-translational modifications (PTMs) have been central to our und...
We have tested the specificity and utility of more than 200 antibodies raised against 57 different h...
Post-translational modifications (PTMs) of histones constitute a major chromatin indexing mechanism,...
Access to high quality antibodies is a necessity for the study of histones and their posttranslation...
We report a general method to examine the recognition of post-translational modifications (PTMs) by ...
We present here the very robust characterization and quality control (QC) process that we have estab...
BackgroundThe robustness of ChIP-seq datasets is highly dependent upon the antibodies used. Currentl...
Antibodies directed against histone posttranslational modifications (PTMs) are critical tools in epi...
In the eukaryotic genome, DNA is organized into nucleosomes, which are comprised by 147bp of DNA wra...
Imagine you’re just starting in a lab. Your new PI decides to test your mettle at the bench with a s...
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure ...
SummaryIncreasing evidence suggests that histone posttranslational modifications (PTMs) function in ...
Problems with antibody quality have been described in numerous recent publications. In the present c...
Research antibodies are used in a wide range of bioscience disciplines, yet it is common to hear dis...
Antibodies are critical reagents to detect and characterize proteins. It is commonly understood that...
Antibodies specific for histone post-translational modifications (PTMs) have been central to our und...