Background: The gold standard treatment for chronic hepatitis C virus (HCV) infection is pegylated interferon (PEG-IFN) in combination with ribavirin. Most patients treated with PEG-IFN achieve a sustained virological response (SVR). However host genetic factors play a vital role in the spontaneous and treatment-induced clearance of HCV infection from these infected patients. In the current study, polymorphisms of IL28B (rs8099917 and rs12979860) were analyzed and their association with the virological response to PEG-IFN alpha treatment was determined. Methods: One hundred and fifty HCV genotype 3 patients were assessed to study the correlation of IL28B with a therapeutic regimen of PEG-IFN alpha plus ribavirin. Twenty patients were exclud...
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the i...
Introduction. The treatment of hepatitis C virus (HCV) genotype 1 with ribavirin (RBV) and pegylated...
PubMedID: 25857516Background and objective: The hepatitis C virus (HCV) which infects 3% of the worl...
SummaryBackgroundThe gold standard treatment for chronic hepatitis C virus (HCV) infection is pegyla...
BACKGROUND AND AIMS: Genetic polymorphisms near interleukin 28B gene are associated with spontaneous...
Background and Aims: Genetic polymorphisms near interleukin 28B gene are associated with spontaneous...
Background: The present study aimed to determine the frequency of the IL28B polymorphism rs8099917 i...
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated wit...
Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue ...
Polymorphisms near the IL28B gene, which code for interferon (IFN)-lambda 3, predict response to peg...
Background and objective: Interleukin (IL) 28B single nucleotide polymorphisms (SNP) was recently re...
Background: Genome wide association studies elucidate that IL28B rs12979860 genetic polymorphism has...
Background: It has been shown that single nucleotide polymorphisms (SNPs) near the interleukin 28B (...
AbstractThere are over 10 million hepatitis C virus (HCV)-infected patients in Pakistan. For these p...
Background: Chronic hepatitis C virus (HCV) represents one of the common causes of chronic liver dis...
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the i...
Introduction. The treatment of hepatitis C virus (HCV) genotype 1 with ribavirin (RBV) and pegylated...
PubMedID: 25857516Background and objective: The hepatitis C virus (HCV) which infects 3% of the worl...
SummaryBackgroundThe gold standard treatment for chronic hepatitis C virus (HCV) infection is pegyla...
BACKGROUND AND AIMS: Genetic polymorphisms near interleukin 28B gene are associated with spontaneous...
Background and Aims: Genetic polymorphisms near interleukin 28B gene are associated with spontaneous...
Background: The present study aimed to determine the frequency of the IL28B polymorphism rs8099917 i...
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated wit...
Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue ...
Polymorphisms near the IL28B gene, which code for interferon (IFN)-lambda 3, predict response to peg...
Background and objective: Interleukin (IL) 28B single nucleotide polymorphisms (SNP) was recently re...
Background: Genome wide association studies elucidate that IL28B rs12979860 genetic polymorphism has...
Background: It has been shown that single nucleotide polymorphisms (SNPs) near the interleukin 28B (...
AbstractThere are over 10 million hepatitis C virus (HCV)-infected patients in Pakistan. For these p...
Background: Chronic hepatitis C virus (HCV) represents one of the common causes of chronic liver dis...
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the i...
Introduction. The treatment of hepatitis C virus (HCV) genotype 1 with ribavirin (RBV) and pegylated...
PubMedID: 25857516Background and objective: The hepatitis C virus (HCV) which infects 3% of the worl...