The concept of entropy spatial-energy interactions is used to reflect the similar views on the statistical thermodynamics of entropy. The resulting nomogram is obtained for estimating the entropy of various processes. The authors discuss the variety of manifestations of entropy, including the biochemical processes in the economy. In living systems the entropy increase is offset by the negative entropy, which is formed through interaction with the external environment. Thus, a living system is an open system. And businesses can no longer be isolated systems without exchange process and the relationship with the external environment. The role of the external system reducing the increase in business entropy must perform, for example, rel...