Incomplete Kawasaki disease - a diagnostic and therapeutic challenge

<p><strong>Background <br /> </strong>The diagnosis of classical Kawasaki Disease was based on clinical criteria. The conventional criteria is particularly useful in preventing over diagnosis, but at the same time it may result in failure to recognize the incomplete form of Kawasaki Disease.</p> <p><strong>Objective <br /> </strong>To suspect incomplete Kawasaki Disease, because early diagnosis and proper treatment may reduce substantial risk of developing coronary artery abnormality which is one of the leading causes of acquired heart disease in children.</p> <p><strong>Method <br /> </strong>Nine cases of incomplete Kawasaki Disease were diagnosed over a period of one year. The diagnosis of incomplete Kawasaki Disease was based on fever for five days with less than four classical clinical features and cardiac abnormality detected by 2D- echocardiography. A repeat echocardiography was done after 6 weeks of onset of illness. The patients were treated with Intravenous Immunoglobulin and/or aspirin.</p> <p><strong>Result <br /> </strong>The mean age of the patients was 3.83 years and the mean duration of symptoms before diagnosis was 12.1 days. Apart from other criteria all of our patients had edema and extreme irritability. All the patients had abnormal echocardiographic finding. Five patients received only aspirin due to nonaffordability of Intravenous Immunoglobulin and four patients received both aspirin and Intravenous Immunoglobulin, but the outcome was excellent in all the cases.</p> <p><strong>Conclusion <br /> </strong>Incomplete Kawasaki Disease can be diagnosed with more awareness and aspirin alone may be used as a second line therapy in case of non affordability of Intravenous Immunoglobulin.</p> <p><em>Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-4, 30-35</em><br /> <br /> DOI:&nbsp;<a href="http://dx.doi.org/10.3126/jcmsn.v9i4.10234">http://dx.doi.org/10.3126/jcmsn.v9i4.10234</a>