Background & aim: CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily which play an important role in the metabolism of many drugs. The CYP2D6 gene presents a high allele heterogeneity that significantly stimulated many changes between individuals in a population, so that classified into extensive, intermediate, or poor drug metabolizers. The CYP2D6*4 allele is the most common polymorphic allele of CYP2D6 gene which due to a nucleotide change of G→A )G1934→A(, resulting in a reduced or lack of activity of CYP iso-enzyme. The aim of this study was to evaluate the frequency of CYP2D6*4 allele among patient and control groups and t...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
OBJECTIVE: Xenobiotic-metabolizing enzymes are widely polymorphic and confer interindividual variati...
Ali Bagheri,1 Behnam Kamalidehghan,2 Maryam Haghshenas,3 Parisa Azadfar,4 Leila Akbari,4 Mohammad Ho...
BACKGROUND: CYP2D6 is an important cytochrome P450 enzyme. These enzymes catalyse the oxidative bio...
Introduction & Objective: Breast cancer is the most frequent malignancy among women worldwide. Poly...
Objective: CYP2D6, an enzyme, metabolizes a large number of commonly prescribed drugs. Variations i...
Background: Genetic polymorphism of CYP2A6 gene is a major causal factor in the large interindividua...
Background: Cytochrome P450 2E1 (CYP2E1) is a main enzyme which plays a major role in activating and...
Context: The growth inhibitory effect of tamoxifen, which is used for the treatment of hormone recep...
CYP2D6 belongs to the cytochrome P450 superfamily of enzymes and plays an important role in the meta...
Background: Cytochrome P450 2C19 (CYP2C19) is a polymorphically expressed enzyme that shows marked i...
PubMedID: 22910059Allele and genotype frequency distribution of CYP2D6*3, *4, *5, *6 and *10 variant...
Drugs and carcinogens are substrates of a group of metabolic enzymes including cytochrome p450 enzym...
AIM: To study the polymorphic variants in CYP2C9*2*3 and the C-174G promoter polymorphism of the IL-...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
OBJECTIVE: Xenobiotic-metabolizing enzymes are widely polymorphic and confer interindividual variati...
Ali Bagheri,1 Behnam Kamalidehghan,2 Maryam Haghshenas,3 Parisa Azadfar,4 Leila Akbari,4 Mohammad Ho...
BACKGROUND: CYP2D6 is an important cytochrome P450 enzyme. These enzymes catalyse the oxidative bio...
Introduction & Objective: Breast cancer is the most frequent malignancy among women worldwide. Poly...
Objective: CYP2D6, an enzyme, metabolizes a large number of commonly prescribed drugs. Variations i...
Background: Genetic polymorphism of CYP2A6 gene is a major causal factor in the large interindividua...
Background: Cytochrome P450 2E1 (CYP2E1) is a main enzyme which plays a major role in activating and...
Context: The growth inhibitory effect of tamoxifen, which is used for the treatment of hormone recep...
CYP2D6 belongs to the cytochrome P450 superfamily of enzymes and plays an important role in the meta...
Background: Cytochrome P450 2C19 (CYP2C19) is a polymorphically expressed enzyme that shows marked i...
PubMedID: 22910059Allele and genotype frequency distribution of CYP2D6*3, *4, *5, *6 and *10 variant...
Drugs and carcinogens are substrates of a group of metabolic enzymes including cytochrome p450 enzym...
AIM: To study the polymorphic variants in CYP2C9*2*3 and the C-174G promoter polymorphism of the IL-...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
Genetic polymorphisms in cytochrome P450 genes can cause alteration in metabolic activity of clinica...
OBJECTIVE: Xenobiotic-metabolizing enzymes are widely polymorphic and confer interindividual variati...