The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimes-conflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date
The ability of histamine H3 receptor ligands to interact with 5-HT3 receptors in NG108-15 cells was ...
The histamine H3 receptor is a G protein-coupled receptor (GPCR) drug target that is highly expresse...
Histamine H receptor antagonists and inverse agonists have been extensively developed to treat sleep...
Histamine is one of the most important biogenic amines and it mediates numbers of physiological proc...
Histamine H3 receptor (H3R) agonists without an imidazole moiety remain very scarce. Of these, ZEL-H...
In this article, we pharmacologically characterized two naturally occurring human histamine H3 recep...
The histamine H-3 receptor (H3R) is an important modulator of numerous central control mechanisms. N...
Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a poten...
AbstractHematopoietic progenitor cells can take up histamine or release IL-3-induced histamine throu...
International audienceConstitutive activity has been mainly recorded for numerous overexpressed and/...
The neurotransmitter histamine exerts its action through four distinct histamine receptors. The hist...
Receptor histaminowy H3 został odkryty w 1983 roku przez Schwartza [1]. Od tego czasu w wielu ośrodk...
International audienceAlthough constitutive activity was shown to occur with many recombinant and/or...
ABSTRACT Previously reported pharmacological studies using the imidazole-containing histamine H 3 re...
Histamine is a transmitter that activates the four receptors H1R to H4R. The H3R is found in the ner...
The ability of histamine H3 receptor ligands to interact with 5-HT3 receptors in NG108-15 cells was ...
The histamine H3 receptor is a G protein-coupled receptor (GPCR) drug target that is highly expresse...
Histamine H receptor antagonists and inverse agonists have been extensively developed to treat sleep...
Histamine is one of the most important biogenic amines and it mediates numbers of physiological proc...
Histamine H3 receptor (H3R) agonists without an imidazole moiety remain very scarce. Of these, ZEL-H...
In this article, we pharmacologically characterized two naturally occurring human histamine H3 recep...
The histamine H-3 receptor (H3R) is an important modulator of numerous central control mechanisms. N...
Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a poten...
AbstractHematopoietic progenitor cells can take up histamine or release IL-3-induced histamine throu...
International audienceConstitutive activity has been mainly recorded for numerous overexpressed and/...
The neurotransmitter histamine exerts its action through four distinct histamine receptors. The hist...
Receptor histaminowy H3 został odkryty w 1983 roku przez Schwartza [1]. Od tego czasu w wielu ośrodk...
International audienceAlthough constitutive activity was shown to occur with many recombinant and/or...
ABSTRACT Previously reported pharmacological studies using the imidazole-containing histamine H 3 re...
Histamine is a transmitter that activates the four receptors H1R to H4R. The H3R is found in the ner...
The ability of histamine H3 receptor ligands to interact with 5-HT3 receptors in NG108-15 cells was ...
The histamine H3 receptor is a G protein-coupled receptor (GPCR) drug target that is highly expresse...
Histamine H receptor antagonists and inverse agonists have been extensively developed to treat sleep...
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