We conducted a genome-wide association study for age at natural menopause in 2,979 European women and identified six SNPs in three loci associated with age at natural menopause: chromosome 19q13.4 (rs1172822; -0.4 year per T allele (39%); P = 6.3 × 10 11), chromosome 20p12.3 (rs236114; +0.5 year per A allele (21%); P = 9.7 × 10 11) and chromosome 13q34 (rs7333181; +0.5 year per A allele (12%); P = 2.5 × 10 8). These common genetic variants regulate timing of ovarian aging, an important risk factor for breast cancer, osteoporosis and cardiovascular disease
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...