Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins
- Wu, T.
- Boezen, H.M.
- Postma, D.S.
- Los, H.
- Postmus, P.E.
- Snieder, H.
- Boomsma, D.I.
Publication date
January 2010
DOIAbstract
It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FE
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