Carbamazepine (CBZ), a widely used anticonvulsant drug, can crystallize and exhibits four polymorphic forms and one dihydrate. Anhydrous CBZ can spontaneously absorb water and convert to the hydrate form whose different crystallinity leads to lower biological activity. The present study was concerned to the possibility of recovering the hydrated form by heating. The thermal behavior of spontaneously hydrated carbamazepine was investigated by TG/DTG-DTA and DSC in dynamic atmospheres of air and nitrogen, which revealed that the spontaneous hydration of this pharmaceutical resulted in a Form III hydrate with 1.5 water molecules. After dehydration, this anhydrous Form III converted to Form I, which melted and decomposed in a single event, rele...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the study of c...
The purpose of this study was to investigate the influence of supercritical CO2 processing on the ph...
A carbamazepina (5H-dibenz[b, f]azepina-5-carboxamida) é um anticonvulsivante frequentemente utiliza...
A carbamazepina (5H-dibenz[b, f]azepina-5-carboxamida) é um anticonvulsivante frequentemente utiliza...
This thesis presents a detailed study into the thermodynamic stability and dehydration kinetics of a...
Physical stability as well as isothermal and non-isothermal cold-crystallization of quench-cooled dr...
Polymorphs of a compound have solid crystalline phases with different internal crystal lattices; in ...
Temperature-induced phase transitions in carbamazepine (CBZ) and 10,11-dihydrocarbamazepine (DHC) we...
This thesis presents a detailed study into the thermodynamic stability and dehydration kinetics of ...
Polymorphs of a compound have solid crystalline phases with different internal crystal lattices; in ...
NoPure anhydrous polymorphs of carbamazepine were prepared by solution-enhanced dispersion with supe...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
ABSTRACT: For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the ...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the study of c...
The purpose of this study was to investigate the influence of supercritical CO2 processing on the ph...
A carbamazepina (5H-dibenz[b, f]azepina-5-carboxamida) é um anticonvulsivante frequentemente utiliza...
A carbamazepina (5H-dibenz[b, f]azepina-5-carboxamida) é um anticonvulsivante frequentemente utiliza...
This thesis presents a detailed study into the thermodynamic stability and dehydration kinetics of a...
Physical stability as well as isothermal and non-isothermal cold-crystallization of quench-cooled dr...
Polymorphs of a compound have solid crystalline phases with different internal crystal lattices; in ...
Temperature-induced phase transitions in carbamazepine (CBZ) and 10,11-dihydrocarbamazepine (DHC) we...
This thesis presents a detailed study into the thermodynamic stability and dehydration kinetics of ...
Polymorphs of a compound have solid crystalline phases with different internal crystal lattices; in ...
NoPure anhydrous polymorphs of carbamazepine were prepared by solution-enhanced dispersion with supe...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
ABSTRACT: For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the ...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
The influence of experimental conditions on polymorphic outcome and transformations during cooling c...
For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the study of c...
The purpose of this study was to investigate the influence of supercritical CO2 processing on the ph...