Objective - To explore to what extent homocysteine, S-adenosylmethionine (SAM), S-adenosylhomocysteine, total folate, 5-methyltetrahydrofolate (5-MTHF), vitamin B12, and vitamin B6 are associated with endothelium-dependent, flow-mediated vasodilation (FMD), and whether these associations are stronger in individuals with diabetes or other cardiovascular risk factors. Methods and Results - In this population-based study of 608 elderly people, FMD and endothelium-independent nitroglycerin-mediated dilation (NMD) were ultrasonically estimated from the brachial artery (absolute change in diameter [μm]). High SAM and low 5-MTHF were significantly associated with high and low FMD, respectively (linear regression coefficient, [95% confidence interv...
A major unanswered question is whether direct cellular toxicity of homocysteine (Hcy) is causally i...
OBJECTIVES: Endothelin-1 (ET-1) is a key regulator of arterial blood pressure in humans, and homocys...
Background. Hyperhomocysteinaemia is an independent risk factor for the development of atheroscleros...
Objective - To explore to what extent homocysteine, S-adenosylmethionine (SAM), S-adenosylhomocystei...
OBJECTIVE: To explore to what extent homocysteine, S-adenosylmethionine (SAM), S-adenosylhomocystein...
): 48.57 microm (21.16; 75.98) and -32.15 microm (-59.09; -5.20), but high homocysteine was not (-15...
Dysfunction of the endothelium is an early event in the pathophysiology of atherosclerosis. Elevated...
Background: Homocysteine is a sulfur-containing intermediate product in the normal metabolism of met...
Objetives: To compare endothelium-dependent vasomotor response in healthy younger and older subjects...
OBJECTIVE: Homocysteinemia is associated with elevated oxidative stress and impaired endothelial fun...
Objective: Hyperhomocysteinemia is a risk factor for atherothrombosis. Through unknown mechanisms, i...
Hyperhomocysteinemia is a risk factor for arterial vascular disease and venous thrombosis. The patho...
The mechanism by which homocysteine (Hcy) causes endothelial dysfunction is probably mediated by oxi...
Background: The relationship between hyperhomocysteinemia and cardiovascular disease has not been to...
Objective: Hyperhomocysteinemia (HHcy) has been identified as an independent risk factor for atheros...
A major unanswered question is whether direct cellular toxicity of homocysteine (Hcy) is causally i...
OBJECTIVES: Endothelin-1 (ET-1) is a key regulator of arterial blood pressure in humans, and homocys...
Background. Hyperhomocysteinaemia is an independent risk factor for the development of atheroscleros...
Objective - To explore to what extent homocysteine, S-adenosylmethionine (SAM), S-adenosylhomocystei...
OBJECTIVE: To explore to what extent homocysteine, S-adenosylmethionine (SAM), S-adenosylhomocystein...
): 48.57 microm (21.16; 75.98) and -32.15 microm (-59.09; -5.20), but high homocysteine was not (-15...
Dysfunction of the endothelium is an early event in the pathophysiology of atherosclerosis. Elevated...
Background: Homocysteine is a sulfur-containing intermediate product in the normal metabolism of met...
Objetives: To compare endothelium-dependent vasomotor response in healthy younger and older subjects...
OBJECTIVE: Homocysteinemia is associated with elevated oxidative stress and impaired endothelial fun...
Objective: Hyperhomocysteinemia is a risk factor for atherothrombosis. Through unknown mechanisms, i...
Hyperhomocysteinemia is a risk factor for arterial vascular disease and venous thrombosis. The patho...
The mechanism by which homocysteine (Hcy) causes endothelial dysfunction is probably mediated by oxi...
Background: The relationship between hyperhomocysteinemia and cardiovascular disease has not been to...
Objective: Hyperhomocysteinemia (HHcy) has been identified as an independent risk factor for atheros...
A major unanswered question is whether direct cellular toxicity of homocysteine (Hcy) is causally i...
OBJECTIVES: Endothelin-1 (ET-1) is a key regulator of arterial blood pressure in humans, and homocys...
Background. Hyperhomocysteinaemia is an independent risk factor for the development of atheroscleros...