Molecular characterization of Enterobacteriaceae resistant to carbapenem antimicrobials
- Jaciane B. Marques
- Pauline C. Bonez
- Vanessa A. Agertt
- Vanessa C. Flores
- Tanise V. Dalmolin
- Grazielle G. Rossi
- Nara Lucia F. Dal Forno
- Bianca V. Bianchini
- Caren R. Mizdal
- Fallon S. Siqueira
- Roselene A. Righi
- Bettina H. Meneghetti
- Priscila A. Trindade
- Roberto C. V. Santos
- Marli M. A. Campos
Publication date
June 2015
DOI Publisher
Sociedade Brasileira de Patologia Clínica ISSN
1676-2444 Journal
1678-4774 Citation count (estimate)
1Abstract
ABSTRACT The present study aimed to genotypically and phenotypically characterize clinical isolates of carbapenem-resistant Enterobacteriaceae collected from inpatients at the University Hospital of Santa Maria, during seven months. Among the clinical isolates subjected to the modified Hodge test (MHT), 62.5% were positive, indicating possible production of carbapenemase. Polymerase chain reaction (PCR) demonstrated that blaKPC was the most frequently found gene (31%), followed by blaIMP (12.5%). Combined use of the methods is needed to identify carbapenem resistance in enterobacteria to prevent their spread and control the infections caused by these organisms
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