Carotid artery intima-media thickness, but not coronary artery calcium, predicts vascular resistance in patients evaluated for coronary artery disease
- Danad, I.
- Raijmakers, P.G.
- Kamali, P.
- Harms, H.J.
- de Haan, S.
- Lubberink, J.M.
- van Kuijk, C.
- Hoekstra, O.S.
- Lammertsma, A.A.
- Smulders, Y.M.
- Heijmans, M.W.
- Tulevski, I.I.
- van Rossum, A.C.
- Knaapen, P.
DOIAbstract
Aims: There is growing evidence that coronary artery disease (CAD) affects not only the conduit epicardial coronary arteries, but also the microvascular coronary bed. Moreover, coronary microvascular dysfunction (CMVD) often precedes the stage of clinically overt epicardial CAD. Coronary artery calcium (CAC) and carotid intima-media thickness (C-IMT) measured with computed tomography (CT) and ultrasound, respectively, are among the available techniques to non-invasively assess atherosclerotic burden. An increased CAC score and C-IMT have also been associated with CMVD. It is therefore of interest to explore and compare the potential of CAC against C-IMT to predict minimal coronary vascular resistance (CVR). Methods and results: We evaluated...
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