Synthesis, characterization, antibacterial and antiepileptic studies of some novel thiazolidinone derivatives

In the quest of finding new drug leads with potential antibacterial and antiepileptic activities, synthesis of thiazolidinone derivatives 6(a–c) is reported which are obtained from 5-(4-chlorobenzylidine)-3-[4-(7-chloroquinoline-4-ylamino]propyl)-2-imino-thiazolidin-4-one derivatives by applying appropriate synthetic route. These compounds 6(a–c) were evaluated for antibacterial and antiepileptic activities. Compound 6a having good lipophilicity is found to be most active