Human language emerged abruptly. Diverse body forms evolved suddenly. Seed-bearing plants spread rapidly. How do complex evolutionary innovations arise so quickly? Resolving alternative claims remains difficult. The great events of the past happened a long time ago. Cancer provides a model to study evolutionary innovation. A tumor must evolve many novel traits to become an aggressive cancer. I use what we know or could study about cancer to describe the key processes of innovation. In general, evolutionary systems form a hierarchy of recursive processes. Those recursive processes determine the rates at which innovations are generated, spread and transmitted. I relate the recursive processes to abrupt evolutionary innovation
Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contr...
One of the major developments in cancer research in recent years has been the construction of models...
International audienceSince the mid 1970s, cancer has been described as a process of Darwinian evolu...
Human language emerged abruptly. Diverse body forms evolved suddenly. Seed-bearing plants sprea...
One of the major stumbling blocks to understanding evolution is the difficulty in reconciling the em...
Paraphrasing Dobzhansky's famous dictum, I discuss how interrogating cancer through the lens of evol...
The evolution of life from the simplest, original form to complex, intelligent animal life occurred ...
Evolutionary dynamics of cancer Evolutionary dynamics of mutation and selection can be formulated by...
Cancer mostly is a disease of old age. Evolutionary pressures have pushed the somatic "error rate", ...
International audienceThe evolutionary perspective of cancer (which origins and dynamics result from...
Evolution and development are both lineage processes but are often conceptualized as occurring by di...
Biological evolution and technological innovation, while differing in many respects, also share comm...
There is an active research program currently underway, which treats cancer progression as an evolut...
Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contr...
One of the major developments in cancer research in recent years has been the construction of models...
International audienceSince the mid 1970s, cancer has been described as a process of Darwinian evolu...
Human language emerged abruptly. Diverse body forms evolved suddenly. Seed-bearing plants sprea...
One of the major stumbling blocks to understanding evolution is the difficulty in reconciling the em...
Paraphrasing Dobzhansky's famous dictum, I discuss how interrogating cancer through the lens of evol...
The evolution of life from the simplest, original form to complex, intelligent animal life occurred ...
Evolutionary dynamics of cancer Evolutionary dynamics of mutation and selection can be formulated by...
Cancer mostly is a disease of old age. Evolutionary pressures have pushed the somatic "error rate", ...
International audienceThe evolutionary perspective of cancer (which origins and dynamics result from...
Evolution and development are both lineage processes but are often conceptualized as occurring by di...
Biological evolution and technological innovation, while differing in many respects, also share comm...
There is an active research program currently underway, which treats cancer progression as an evolut...
Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contr...
One of the major developments in cancer research in recent years has been the construction of models...
International audienceSince the mid 1970s, cancer has been described as a process of Darwinian evolu...