Impact of aortic valve sclerosis on clinical outcome in patients undergoing elective PCI using bare metal stents

Background: Prevalence of aortic valve sclerosis (AVS) increases with age. AVS is associated with adverse cardiovascular events. The present study aimed to evaluate the association between AVS and adverse events in patients undergoing elective percutaneous coronary intervention (PCI) using bare metal stents (BMS). Methods: The study included 200 consecutive patients who underwent elective (PCI) using BMS. Echocardiographic study was done for evaluation of the presence or absence of AVS. Patients were followed for 6 months. Major adverse cardiovascular events were defined as cardiac death, acute myocardial infarction (AMI), and stent thrombosis and target lesion revascularization. Total MACE was defined as in hospital and 6-month follow-up MACE. Results: Of the 200 patients included in the study, 58 patients (29%) were found to have AVS. The presence of AVS was associated with a higher prevalence of cardiovascular risk factors. The total MACE rate was significantly higher in patients with AVS than those with no AVS (44.8% vs. 24.6%, P = 0.0082). Using multivariable logistic regression analysis for adjustment of the baseline and echocardiographic characteristics, the association between AVS and adverse events remained significant (odd ratio = 0.30; 95% confidence interval, 0.11–0.826). Conclusion: AVS is associated with increased morbidity and mortality in patients undergoing elective PCI using BMS