Pancreatic islet transplantation is performed as a potential treatment for type 1 diabetes mellitus. However, this approach is significantly limited due to the critical shortage of islet sources. Recently, a number of publications have developed protocols for directed β-cell differentiation of pluripotent cells, such as embryonic stem (ES) or induced pluripotent stem (iPS) cells. Decades of studies have led to the development of modified protocols that recapitulate molecular developmental cues by combining various growth factors and small molecules with improved efficiency. However, the later step of pancreatic differentiation into functional β-cells has yet to be satisfactory in vitro, highlighting alternative approach by recapitulating sp...
There are a lot of diseases caused by tissue degeneration or errors in the organs. Current treatment...
Since insulin discovery, islet transplantation was the first protocol to show the possibility to cur...
Abstract Among the different approaches for diabetes mellitus-pancreas and pancreatic islet transpl...
AbstractPancreatic islet transplantation is performed as a potential treatment for type 1 diabetes m...
Abstract Recent advances in the expansion and directed pancreatogenic differentiation of human pluri...
Type 1 diabetes mellitus (T1DM) is a form of diabetes that inhibits or halts insulin production in t...
Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered...
Differentiation of human pluripotent stem cells into pancreatic beta cells could lead to the develop...
According to Centers of Disease Control (CDC), 25.8 million Americans were diagnosed with diabetes i...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
Efficiently obtaining functional pancreatic islet cells derived from human embryonic stem (hES) cell...
In the context of a cellular therapy for diabetes, methods for pancreatic progenitor expansion and s...
Abstract Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune destruct...
There are a lot of diseases caused by tissue degeneration or errors in the organs. Current treatment...
Since insulin discovery, islet transplantation was the first protocol to show the possibility to cur...
Abstract Among the different approaches for diabetes mellitus-pancreas and pancreatic islet transpl...
AbstractPancreatic islet transplantation is performed as a potential treatment for type 1 diabetes m...
Abstract Recent advances in the expansion and directed pancreatogenic differentiation of human pluri...
Type 1 diabetes mellitus (T1DM) is a form of diabetes that inhibits or halts insulin production in t...
Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered...
Differentiation of human pluripotent stem cells into pancreatic beta cells could lead to the develop...
According to Centers of Disease Control (CDC), 25.8 million Americans were diagnosed with diabetes i...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
The transplantation of pancreatic islets is promising treatment for patients of type 1 diabetes, suf...
Efficiently obtaining functional pancreatic islet cells derived from human embryonic stem (hES) cell...
In the context of a cellular therapy for diabetes, methods for pancreatic progenitor expansion and s...
Abstract Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune destruct...
There are a lot of diseases caused by tissue degeneration or errors in the organs. Current treatment...
Since insulin discovery, islet transplantation was the first protocol to show the possibility to cur...
Abstract Among the different approaches for diabetes mellitus-pancreas and pancreatic islet transpl...