Imaging characterization of cryptococcal meningoencephalitis

Cryptococcus neoformans is the most common opportunistic CNS fungal pathogen in HIV-positive patients. About 7%–8% of the HIV-positive patients will have cryptococcal meningoencephalitis. Imaging plays an important role in the evaluation of cryptococcal infection of the brain. Abnormal findings correlated with higher risk of death. The paper will review the pathogenesis, pathology, imaging characterization and complication combined with cryptococcal meningoencephalitis