Confocal endomicroscopy is a powerful tool for in vivo real-time imaging at cellular resolution inside a living body without tissue resection. Microscopic fluorescence lifetime measurement can provide information about localized biochemical conditions such as pH and the concentrations of oxygen and calcium. We hypothesized that combining these techniques could assist accurate cancer discrimination by providing both biochemical and morphological information. We designed a dual-mode experimental setup for confocal endomicroscopic imaging and fluorescence lifetime measurement and applied it to a mouse xenograft model of activated human pancreatic cancer generated by subcutaneous injection of AsPC-1 tumor cells. Using this method with pH-sensit...
In this paper we demonstrate results of combined measurements by diffuse reflectance and fluorescenc...
The use of fluorescent proteins to label tumors is revolutionizing cancer research, enabling imaging...
Fluorescence intensity measurements in cellular microscopy have become a valuable tool for resolving...
AbstractConfocal endomicroscopy is a powerful tool for in vivo real-time imaging at cellular resolut...
Confocal endomicroscopy is a powerful tool for in vivo real-time imaging at cellular resolution insi...
Confocal fluorescence endomicroscopes employ fibre optics along with miniaturised scanning and focus...
Abstract A biopsy is often performed for the diagnosis of cancer during a surgical operation. In add...
Tissue characterization by endoscopic fluorescence imaging of endogenous or exogenous fluorochromes ...
We describe a new fluorescence imaging device for clinical cancer photodetection in hollow organs in...
Tumor detection has been carried out in mice sensitized with hematoporphyrin derivative (HpD) by mea...
Abstract The classical examination of histology slides from a mouse model of breast cancer has been ...
Fluorescence lifetime imaging (FLIM) depends on the fluorescence decay differences between tissues t...
Fluorescence lifetime imaging (FLIM) depends on the fluorescence decay differences between tissues t...
An optical imaging and spectroscopy system has been developed for the study of in vivo fluorescence ...
Mouse models are essential tools for understanding cancer growth and accelerating the development of...
In this paper we demonstrate results of combined measurements by diffuse reflectance and fluorescenc...
The use of fluorescent proteins to label tumors is revolutionizing cancer research, enabling imaging...
Fluorescence intensity measurements in cellular microscopy have become a valuable tool for resolving...
AbstractConfocal endomicroscopy is a powerful tool for in vivo real-time imaging at cellular resolut...
Confocal endomicroscopy is a powerful tool for in vivo real-time imaging at cellular resolution insi...
Confocal fluorescence endomicroscopes employ fibre optics along with miniaturised scanning and focus...
Abstract A biopsy is often performed for the diagnosis of cancer during a surgical operation. In add...
Tissue characterization by endoscopic fluorescence imaging of endogenous or exogenous fluorochromes ...
We describe a new fluorescence imaging device for clinical cancer photodetection in hollow organs in...
Tumor detection has been carried out in mice sensitized with hematoporphyrin derivative (HpD) by mea...
Abstract The classical examination of histology slides from a mouse model of breast cancer has been ...
Fluorescence lifetime imaging (FLIM) depends on the fluorescence decay differences between tissues t...
Fluorescence lifetime imaging (FLIM) depends on the fluorescence decay differences between tissues t...
An optical imaging and spectroscopy system has been developed for the study of in vivo fluorescence ...
Mouse models are essential tools for understanding cancer growth and accelerating the development of...
In this paper we demonstrate results of combined measurements by diffuse reflectance and fluorescenc...
The use of fluorescent proteins to label tumors is revolutionizing cancer research, enabling imaging...
Fluorescence intensity measurements in cellular microscopy have become a valuable tool for resolving...