Clinical study on the treatment of PDR with cataract by vitreous cavity injection and intraocular lens implantation

AIM: To evaluate the clinical effect of phacoemulsification and intraocular lens(IOL)implantation in the treatment of proliferative diabetic retinopathy(PDR)with cataract. <p>METHODS: Totally 261 patients(266 eyes)with PDR complicated with cataract in our hospital were selected and randomly divided into control group(133 eyes in 130 patients)and study group(133 eyes in 131 patients). The control group underwent vitrectomy combined with laser photocoagulation, phacoemulsification and intraocular lens implantation. The study group received intravitreal injection of bevacizumab before vitrectomy, laser photocoagulation, phacoemulsification and intraocular lens implantation. Clinical curative effect of two groups was analyzed. <p>RESULTS: The postoperative complications of the control group were higher than that of the study group, and the difference was statistically significant(<i>P</i><0.05). In study group, 67 eyes received photocoagulation again, iris neovascularization occurred in none eyes. In control group, 76 eyes received photocoagulation again, iris neovascularization occurred in 17 eyes(22.4%).The difference between the two groups was significant(<i>P</i><0.05). The visual acuity of the study group was better than that of the control group(<i>P</i><0.05). The incidence of macular edema in the control group was significantly higher than that in the study group(<i>P</i><0.05).<p>CONCLUSION: Intravitreal injection of bevacizumab with vitrectomy, phacoemulsification and IOL implantation for cataract has good clinical effect for PDR