Analysis on therapy efficacy of different drugs for dry eyes after cataract surgery

AIM: To explore the therapy efficacy of different drugs for dry eyes after cataract surgery.<p>METHODS: Collected from June 2014 to June 2016 in patients with dry eyes in our departments of cataract surgery, a total of 60 cases with 120 eyes, according to the doctor order divided into pure sodium hyaluronate eye drops group 20 cases(40 eyes, sodium hyaluronate eye drops combined pranoprofen eye drops group 20 cases(40 eyes), sodium hyaluronate eye drops combined pranoprofen eye drops and Qiju Dihuang pill group of 20 cases(40 eyes). All patients were treated for 1mo. Observation of break up time(BUT), Shimmer Ⅰ test(SIt)and fluorescein corneal staining(FI)were recorded before the treatment and 1, 2wk, 1, 3mo after treatment. <p>RESULTS: Difference of efficient rates of three groups 1mo after treatment were statistically significant(<i>P</i><0.05). BUT: there was no statistically significant difference among three groups before treatment(<i>P</i>>0.05); at 1, 3mo after treatment compared with before treatment, the differences of the three groups were statistically significant(<i>P</i><0.05); among the three groups 1, 2wk and 1mo after treatment, the differences were statistically significant(<i>P</i><0.05); at 3mo after treatment the difference among the three groups was not statistically significant(<i>P</i>>0.05); but sodium hyaluronate eye drops combined pranoprofen eye drops and Qiju Dihuang pill group(12.14±1.97s)was superior to pure sodium hyaluronate eye drops group(10.54±1.88s)and sodium hyaluronate eye drops combined pranoprofen eye drops group(12.05±1.63s).SIt: there was no statistically significant difference among three groups before treatment(<i>P</i>>0.05); at 1, 3mo after treatment compared with before treatment, the differences of the three groups were statistically significant(<i>P</i><0.05); among the three groups 1, 2wk and 1mo after treatment, the differences were statistically significant(<i>P</i><0.05); but sodium hyaluronate eye drops combined pranoprofen eye drops and Qiju Dihuang pill group(14.24±1.89mm/5min)was superior to pure sodium hyaluronate eye drops group(12.22±2.54mm/5min)and sodium hyaluronate eye drops combined pranoprofen eye drops group(12.27±2.31mm/5 min).FL: there was no statistically significant difference among three groups before treatment(<i>P</i>>0.05); at 1, 3mo after treatment compared with before treatment, the differences of the three groups were statistically significant(<i>P</i><0.05); among the three groups 1, 2wk and 1mo after treatment, the differences were statistically significant(<i>P</i><0.05); at 3mo after treatment the difference among the three groups was not statistically significant(<i>P</i>>0.05).<p>CONCLUSION:Sodium hyaluronate eye drops combined pranoprofen eye drops and Qiju Dihuang pill in the treatment of dry eye after cataract surgery is better than that of sodium hyaluronate eye drops combined pranoprofen eye drops group and simple application of sodium hyaluronate eye drops, which can better improve the visual function, improve tear film stability, get better treatment effect