Prevalence and antimicrobial susceptibility of genital Mycoplasmas detected by Mycoplasma IST 2 from urogenital samples in Padua, Italy, between January 2014 and December 2015

<em>Background and aims.</em> The aim of this study is to define the epidemiology and the antimicrobial resistance profile of <em>Ureaplasma</em> spp. and <em>Mycoplasma hominis</em> isolated from urogenital specimens of patients attending the Microbiology and Virology Unit of Padua between January 2014 and December 2015. <br /><em>Materials and methods</em>. The analysis was carried out on a total of 10861 samples. Species identification and antimicrobial susceptibility tests were performed using bioMérieux Mycoplasma IST 2. <br /><em>Results</em>. 2668 samples (24.6%) from 2043 patients were positive: 2466 samples positive for <em>Ureaplasma</em> spp. (1897 patients) and 8 samples positive for <em>M. hominis</em> (8 patients), while in 194 samples (138 patients) was detected a coinfection. As for antimicrobial susceptibility of <em>Ureaplasma</em> spp. we found a resistance (R+I) rate of 90.6% for ciprofloxacin, of 74,1% for ofloxacin, of 52.8% for azithromycin and of 47.0% for erythromycin.<br /><em>Conclusions</em>. Our report shows a high prevalence of <em>Ureaplasma</em> spp. in the study population. Surveillance of antibiotic resistance is critical for an appropriate therapeutic approach, which must always be contextualized with patient’s symptomatology