The zebrafish (Danio rerio) is a powerful vertebrate model to study cellular and developmental processes in vivo. The optical clarity and their amenability to genetic manipulation make zebrafish a model of choice when it comes to applying optical techniques involving genetically encoded photoresponsive protein technologies. In recent years, a number of fluorescent protein and optogenetic technologies have emerged that allow new ways to visualize, quantify, and perturb developmental dynamics. Here, we explain the principles of these new tools and describe some of their representative applications in zebrafish
A central goal of Neuroscience is to understand how the brain processes sensory stimuli and generate...
The zebrafish is a recent vertebrate model system that shows great potential for a genetic analysis ...
In the last decades, the tropical teleost zebrafish (Danio rerio) has proved to be an excellent vert...
The zebrafish ( Danio rerio) is a powerful vertebrate model to study cellular and developmental proc...
Optogenetics, the use of light-based protein tools, has begun to revolutionize biological research. ...
In the last years, we have seen the emergence of different tools that have changed the face of biolo...
The Author(s) 2013. This article is published with open access at Springerlink.com Abstract In the l...
In recent years, the zebrafish (Danio rerio) has proved to be an excellent model organism for the a...
Expression of halorhodopsin (NpHR), a light-driven microbial chloride pump, allows for optical contr...
AbstractThe recent explosion of transgenic zebrafish lines in the literature demonstrates the value ...
Optogenetic tools can be used to manipulate neuronal activity in a reversible and specific manner. I...
Basic research in pattern formation is concerned with the generation of phenotypes and tissues. It c...
AbstractThe recent development of transgenic technology in zebrafish has opened an exciting new aven...
BACKGROUND: Elucidating the complex cell dynamics (divisions, movement, morphological changes, etc.)...
In the post genome era, a major goal in molecular biology is to determine the function of the many t...
A central goal of Neuroscience is to understand how the brain processes sensory stimuli and generate...
The zebrafish is a recent vertebrate model system that shows great potential for a genetic analysis ...
In the last decades, the tropical teleost zebrafish (Danio rerio) has proved to be an excellent vert...
The zebrafish ( Danio rerio) is a powerful vertebrate model to study cellular and developmental proc...
Optogenetics, the use of light-based protein tools, has begun to revolutionize biological research. ...
In the last years, we have seen the emergence of different tools that have changed the face of biolo...
The Author(s) 2013. This article is published with open access at Springerlink.com Abstract In the l...
In recent years, the zebrafish (Danio rerio) has proved to be an excellent model organism for the a...
Expression of halorhodopsin (NpHR), a light-driven microbial chloride pump, allows for optical contr...
AbstractThe recent explosion of transgenic zebrafish lines in the literature demonstrates the value ...
Optogenetic tools can be used to manipulate neuronal activity in a reversible and specific manner. I...
Basic research in pattern formation is concerned with the generation of phenotypes and tissues. It c...
AbstractThe recent development of transgenic technology in zebrafish has opened an exciting new aven...
BACKGROUND: Elucidating the complex cell dynamics (divisions, movement, morphological changes, etc.)...
In the post genome era, a major goal in molecular biology is to determine the function of the many t...
A central goal of Neuroscience is to understand how the brain processes sensory stimuli and generate...
The zebrafish is a recent vertebrate model system that shows great potential for a genetic analysis ...
In the last decades, the tropical teleost zebrafish (Danio rerio) has proved to be an excellent vert...