High-strain mylonitic rocks in Cordilleran metamorphic core complexes reflect ductile deformation in the middle crust, but in many examples it is unclear how these mylonites relate to the brittle detachments that overlie them. Field observations, microstructural analyses, and thermobarometric data from the footwalls of three metamorphic core complexes in the Basin and Range Province, USA (the Whipple Mountains, California; the northern Snake Range, Nevada; and Ruby Mountains–East Humboldt Range, Nevada), suggest the presence of two distinct rheological transitions in the middle crust: (1) the brittle–ductile transition (BDT), which depends on thermal gradient and tectonic regime, and marks the switch from discrete brittle faulting and catac...