The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequent airway hyper-responsiveness, is a leading cause of morbidity and mortality in critically ill patients. Several studies have shown that oxidative stress plays a key role in initiation as well as amplification of inflammation in airways. However, still there are no good anti-oxidant strategies available for therapeutic intervention in asthma pathogenesis. Most recent studies suggest that polyol pathway enzyme, aldose reductase (AR), contributes to the pathogenesis of oxidative stress-induced inflammation by affecting the NF-kappaB-dependent expression of cytokines and chemokines and therefore inhibitors of AR could be anti-inflammatory. Since...
Background: Resolution of an inflammatory response is in part an active and controlled process. Rece...
Allergic asthma is an inflammatory disease of the airways and is characterised by chronic inflammati...
Asthma currently affects more than 339 million people worldwide. In the present preliminary study, w...
The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequen...
The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequen...
Background: Long-term and unresolved airway inflammation and airway remodeling, characteristic featu...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
BACKGROUND: Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lu...
.Metaplasia in primary human small airway epithelial cells (SAEC) was induced by a Th2 cytokine, IL-...
AIM: Chronic airway diseases such as asthma are associated with increased production of reactive oxy...
Objective Asthma is a chronic inflammatory disease that can lead to severe problems with the respira...
Exaggerated inflammatory responses and the resultant increases in alveolar-capillary permeability un...
Oxidative stress appears to have an important role in glucocorticoid insensitivity, as a crucial pro...
Background: Resolution of an inflammatory response is in part an active and controlled process. Rece...
Allergic asthma is an inflammatory disease of the airways and is characterised by chronic inflammati...
Asthma currently affects more than 339 million people worldwide. In the present preliminary study, w...
The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequen...
The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequen...
Background: Long-term and unresolved airway inflammation and airway remodeling, characteristic featu...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chron...
BACKGROUND: Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lu...
.Metaplasia in primary human small airway epithelial cells (SAEC) was induced by a Th2 cytokine, IL-...
AIM: Chronic airway diseases such as asthma are associated with increased production of reactive oxy...
Objective Asthma is a chronic inflammatory disease that can lead to severe problems with the respira...
Exaggerated inflammatory responses and the resultant increases in alveolar-capillary permeability un...
Oxidative stress appears to have an important role in glucocorticoid insensitivity, as a crucial pro...
Background: Resolution of an inflammatory response is in part an active and controlled process. Rece...
Allergic asthma is an inflammatory disease of the airways and is characterised by chronic inflammati...
Asthma currently affects more than 339 million people worldwide. In the present preliminary study, w...