Does Neutrophil-to-Lymphocyte Ratio Has a Value in Predicting BCG Recurrence in Bladder Tumor Patients

Aim: To evaluate the prognostic value of preoperative neutrophil to lymphocyte ratio after intravesical Bacillus Calmette-Guérin (BCG) treatment in non-muscle-invasive bladder cancer (NMIBC). Material and Method: The data of 70 patients, operated for urothelial carcinoma and treated with BCG after the diagnose of NMIBC at Türkiye Yüksek Ihtisas Hastanesi between 2007-2013, were reviewed retrospectively. Patients’ preoperative complete blood counter results and first cystoscopic examination findings were recorded.Results: Median follow-up was 26 months. Tumor recurrence was identified at 26 patients (Group 2) among the 70 patients. In 44 patients there was no tumor recurrence (Group 1).  Neutrophil/lyphocyte ratio, multiplicity of tumor and cis frequency were increased statistically in Group 2 (P=0.001, P=0.005, P=0.007, respectively). Discussion: This study showed that, preoperative high neutrophil/lyphocyte ratio, multiplicity of tumor and cis precence can be used as independent criterias for predicting tumor recurrence after intravesical Bacillus Calmette-Guérin (BCG) treatment in NMIBC