In this paper, we demonstrate the feasibility of using in situ Dynamic Light Scattering (DLS) to monitor counter-diffusion crystallization experiments in capillaries. Firstly, we have validated the quality of the DLS signal in thin capillaries, which is comparable to that obtained in standard quartz cuvettes. Then, we have carried out DLS measurements of a counter-diffusion crystallization experiment of glucose isomerase in capillaries of different diameters (0.1, 0.2 and 0.3 mm) in order to follow the temporal evolution of protein supersaturation. Finally, we have compared DLS data with optical recordings of the progression of the crystallization front and with a simulation model of counter-diffusion in 1D
Protein aggregation is a phenomenon that plays a major role in protein crystallization and in protei...
An optical diagnostic system consisting of a Mach-Zehnder interferometer with an image processor was...
The crystallisation by counterdiffusion is a very efficient technique for obtaining high-quality pro...
<div><p>In this paper, we demonstrate the feasibility of using <em>in situ</em> Dynamic Light Scatte...
ABSTRACT: A combined imaging and dynamic light scattering (DLS) system has been developed for routin...
AbstractCrystallization of lysozymes induced by temperature lowering has been monitored by dynamic l...
Success in determining the three-dimensional structure of a macromolecule by X-ray diffraction metho...
AbstractCrystallization of lysozymes induced by temperature lowering has been monitored by dynamic l...
This paper reports that an optical diagnostic system consisting of Mach-Zehnder interferometer with ...
This paper reports that an optical diagnostic system consisting of Mach-Zehnder interferometer with ...
The broad objective of my research is to investigate the physical characteristics and interactions o...
We report an efficient screening methodology based on the capillary counter-diffusion technique (CCD...
The broad objective of my research is to investigate the physical characteristics and interactions o...
The broad objective of my research is to investigate the physical characteristics and interactions o...
We report an efficient screening methodology based on the capillary counter-diffusion technique (CCD...
Protein aggregation is a phenomenon that plays a major role in protein crystallization and in protei...
An optical diagnostic system consisting of a Mach-Zehnder interferometer with an image processor was...
The crystallisation by counterdiffusion is a very efficient technique for obtaining high-quality pro...
<div><p>In this paper, we demonstrate the feasibility of using <em>in situ</em> Dynamic Light Scatte...
ABSTRACT: A combined imaging and dynamic light scattering (DLS) system has been developed for routin...
AbstractCrystallization of lysozymes induced by temperature lowering has been monitored by dynamic l...
Success in determining the three-dimensional structure of a macromolecule by X-ray diffraction metho...
AbstractCrystallization of lysozymes induced by temperature lowering has been monitored by dynamic l...
This paper reports that an optical diagnostic system consisting of Mach-Zehnder interferometer with ...
This paper reports that an optical diagnostic system consisting of Mach-Zehnder interferometer with ...
The broad objective of my research is to investigate the physical characteristics and interactions o...
We report an efficient screening methodology based on the capillary counter-diffusion technique (CCD...
The broad objective of my research is to investigate the physical characteristics and interactions o...
The broad objective of my research is to investigate the physical characteristics and interactions o...
We report an efficient screening methodology based on the capillary counter-diffusion technique (CCD...
Protein aggregation is a phenomenon that plays a major role in protein crystallization and in protei...
An optical diagnostic system consisting of a Mach-Zehnder interferometer with an image processor was...
The crystallisation by counterdiffusion is a very efficient technique for obtaining high-quality pro...