Genetic interaction between donor and recipient may dictate the impending responses after transplantation. In this study, we evaluated the role of the genetic predispositions of stromal-derived factor-1 (SDF1) [rs1801157 (G>A)] and CXC receptor 4 (CXCR4) [rs2228014 (C>T)] on renal allograft outcomes. A total of 335 pairs of recipients and donors were enrolled. Biopsy-proven acute rejection (BPAR) and long-term graft survival were traced. Despite similar allele frequencies between donors and recipients, minor allele of SDF1 rs1801157 (GA+AA) from donor, not from recipients, has a protective effect on the development of BPAR compared to wild type donor (GG) (P = 0.005). Adjustment for multiple covariates did not affect this result (odds rati...
The impact of variation within genes responsible for the disposition and metabolism of calcineurin i...
Background. Vascular endothelial growth factor (VEGF) is crucial for preservation of microvasculatur...
Allelic differences in gene promoter or codifying regions have been described to affect regulation o...
Genetic interaction between donor and recipient may dictate the impending responses after transplant...
Although the genetic polymorphism of Stromal Cell-Derived Factor 1 (SDF-1) is associated with higher...
Donor genomics influence graft events: The effect of donor polymorphisms on acute rejection and chro...
Background. Acute rejection (AR) contributes to the development of chronic allograft nephropathy tha...
Background. Acute allograft rejection remains an important cause of morbidity after kidney transplan...
Background. Certain cytokine gene polymorphisms (CGPs). have been shown to be associated with renal ...
Renal transplant outcomes exhibit large inter-individual variability, possibly on account of genetic...
Chronic rejection is an immune process leading to graft failure. By regulating the trafficking of le...
International audienceWe studied a cohort of 367 healthy related donors who volunteered to donate th...
We studied a cohort of 367 healthy related donors who volunteered to donate their hematopoietic stem...
Artículo de publicación ISIThe modulation of the immune system following solid organ transplantation...
Delayed graft function (DGF) is defined as the need for dialysis within 7 days following kidney tran...
The impact of variation within genes responsible for the disposition and metabolism of calcineurin i...
Background. Vascular endothelial growth factor (VEGF) is crucial for preservation of microvasculatur...
Allelic differences in gene promoter or codifying regions have been described to affect regulation o...
Genetic interaction between donor and recipient may dictate the impending responses after transplant...
Although the genetic polymorphism of Stromal Cell-Derived Factor 1 (SDF-1) is associated with higher...
Donor genomics influence graft events: The effect of donor polymorphisms on acute rejection and chro...
Background. Acute rejection (AR) contributes to the development of chronic allograft nephropathy tha...
Background. Acute allograft rejection remains an important cause of morbidity after kidney transplan...
Background. Certain cytokine gene polymorphisms (CGPs). have been shown to be associated with renal ...
Renal transplant outcomes exhibit large inter-individual variability, possibly on account of genetic...
Chronic rejection is an immune process leading to graft failure. By regulating the trafficking of le...
International audienceWe studied a cohort of 367 healthy related donors who volunteered to donate th...
We studied a cohort of 367 healthy related donors who volunteered to donate their hematopoietic stem...
Artículo de publicación ISIThe modulation of the immune system following solid organ transplantation...
Delayed graft function (DGF) is defined as the need for dialysis within 7 days following kidney tran...
The impact of variation within genes responsible for the disposition and metabolism of calcineurin i...
Background. Vascular endothelial growth factor (VEGF) is crucial for preservation of microvasculatur...
Allelic differences in gene promoter or codifying regions have been described to affect regulation o...