Human pluripotent stem cells (hPSCs), namely, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with their ability of indefinite self-renewal and capability to differentiate into cell types derivatives of all three germ layers, represent a powerful research tool in developmental biology, for drug screening, disease modelling, and potentially cell replacement therapy. Efficient differentiation protocols that would result in the cell type of our interest are needed for maximal exploitation of these cells. In the present work, we aim at focusing on the protocols for differentiation of hPSCs into functional cardiomyocytes in vitro as well as achievements in the heart disease modelling and drug testing on the patient-specif...
Since human embryonic stem cells were first differentiated to beating cardiomyocytes a decade ago, i...
The generation of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes has been of utm...
: Human pluripotent stem cells (hPSCs), derived from individuals or genetically modified with diseas...
More than 10 years after their first isolation, human embryonic stem cells are finally 'coming of ag...
The lack of appropriate human cardiomyocyte-based experimental platform has largely hindered the stu...
More than 10 years after their first isolation, human embryonic stem cells are finally 'coming of ag...
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based on inhere...
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based on inhere...
In the past few years, the use of specific cell types derived from induced pluripotent stem cells (i...
Ventricular cardiac muscle cells, the cardiomyocytes, are the working muscle cells of the heart that...
Ventricular cardiac muscle cells, the cardiomyocytes, are the working muscle cells of the heart that...
Patient-specific induced pluripotent stem (iPS) cells can be generated by introducing transcription ...
The generation of cardiomyocytes from human induced pluripotent stem cells (hiPSCs) provides a sourc...
The invention of the induced pluripotent stem cell (iPSC) technology allows patient-specific, mature...
Embryonic stem (ES) cells are naturally derived from early stage embryos and induced pluripotent ste...
Since human embryonic stem cells were first differentiated to beating cardiomyocytes a decade ago, i...
The generation of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes has been of utm...
: Human pluripotent stem cells (hPSCs), derived from individuals or genetically modified with diseas...
More than 10 years after their first isolation, human embryonic stem cells are finally 'coming of ag...
The lack of appropriate human cardiomyocyte-based experimental platform has largely hindered the stu...
More than 10 years after their first isolation, human embryonic stem cells are finally 'coming of ag...
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based on inhere...
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based on inhere...
In the past few years, the use of specific cell types derived from induced pluripotent stem cells (i...
Ventricular cardiac muscle cells, the cardiomyocytes, are the working muscle cells of the heart that...
Ventricular cardiac muscle cells, the cardiomyocytes, are the working muscle cells of the heart that...
Patient-specific induced pluripotent stem (iPS) cells can be generated by introducing transcription ...
The generation of cardiomyocytes from human induced pluripotent stem cells (hiPSCs) provides a sourc...
The invention of the induced pluripotent stem cell (iPSC) technology allows patient-specific, mature...
Embryonic stem (ES) cells are naturally derived from early stage embryos and induced pluripotent ste...
Since human embryonic stem cells were first differentiated to beating cardiomyocytes a decade ago, i...
The generation of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes has been of utm...
: Human pluripotent stem cells (hPSCs), derived from individuals or genetically modified with diseas...