Uncovering intrinsic modular organization of spontaneous brain activity in humans.
- Yong He
- Jinhui Wang
- Liang Wang
- Zhang J Chen
- Chaogan Yan
- Hong Yang
- Hehan Tang
- Chaozhe Zhu
- Qiyong Gong
- Yufeng Zang
- Alan C Evans
DOIAbstract
The characterization of topological architecture of complex brain networks is one of the most challenging issues in neuroscience. Slow (<0.1 Hz), spontaneous fluctuations of the blood oxygen level dependent (BOLD) signal in functional magnetic resonance imaging are thought to be potentially important for the reflection of spontaneous neuronal activity. Many studies have shown that these fluctuations are highly coherent within anatomically or functionally linked areas of the brain. However, the underlying topological mechanisms responsible for these coherent intrinsic or spontaneous fluctuations are still poorly understood. Here, we apply modern network analysis techniques to investigate how spontaneous neuronal activities in the human brain...
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