Expression of ERα, ERβ and Co-Regulator PELP1/MNAR in Colorectal Cancer: Prognostic Significance and Clinicopathologic Correlations
- Petros D. Grivas
- Vassiliki Tzelepi
- Georgia Sotiropoulou-Bonikou
- Zinovia Kefalopoulou
- Athanasios G. Papavassiliou
- Haralabos Kalofonos
Publication date
January 2009
DOI Publisher
Hindawi Limited Journal
issn:1570-5870Abstract
Background: Estrogen receptor β (ERβ) is abundantly expressed in colorectal tissue, but its role in colorectal carcinogenesis remains elusive. ER novel co-regulator, proline-, glutamic acid- and leucine-rich protein 1 (PELP1/MNAR) has been characterized, but its expression in colorectal carcinomas has not been investigated
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