This paper develops a flexible analytical concept for robust shortest path detection in dynamically reconfigurable graphs. The concept is expressed by a mathematical model representing the shortest path problem solver. The proposed mathematical model is characterized by three fundamental parameters expressing (a) the graph topology (through the “incidence matrix”), (b) the edge weights (with dynamic external weights’ setting capability), and (c) the dynamic reconfigurability through external input(s) of the source-destination nodes pair. In order to demonstrate the universality of the developed concept, a general algorithm is proposed to determine the three fundamental parameters (of the mathematical model developed) for all types of graphs...