Elevated serum triglyceride (TG) and high-density-lipoprotein cholesterol (HDL-C) levels are common in drinkers. The fast-metabolizing alcohol dehydrogenase-1B encoded by the ADH1B*2 allele (vs. ADH1B*1/*1 genotype) and inactive aldehyde dehydrogenase-2 encoded by the ALDH2*2 allele (vs. ALDH2*1/*1 genotype) modify ethanol metabolism and are prevalent (≈90% and ≈40%, respectively) in East Asians. We attempted to evaluate the associations between the ADH1B and ALDH2 genotypes and lipid levels in alcoholics.The population consisted of 1806 Japanese alcoholic men (≥40 years) who had undergone ADH1B and ALDH2 genotyping and whose serum TG, total cholesterol, and HDL-C levels in the fasting state had been measured within 3 days after admission.H...
<p>OR, odds ratio; CI, confidence interval.</p><p>ORs were adjusted for age, usual ethanol consumpti...
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabolism and oxidativ...
Background. Previous population association studies have indicated that certain alleles of alcohol d...
genotype) modify ethanol metabolism and are prevalent (≈90% and ≈40%, respectively) in East Asians....
Background: Although beneficial associations have been reported between moderate alcohol intake and ...
Background: Although beneficial associations have been reported between moderate alcohol intake and ...
Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde dehydrogenase gene ALDH2...
[[abstract]]Background: Alcohol metabolism is one of the biological determinants that can influence ...
Aldehyde dehydrogenase with a low Michaelis constant (Kin), ALDH2, is a major enzyme in-volved in th...
Background: Alcohol consumption has beneficial effects on mortality which are mainly due to reductio...
Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde dehydrogenase gene ALDH2...
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabo-lism and oxidati...
Abstract — Aims: The objective was to clarify the effect of alcohol dehydrogenase 2 (ADH2) and aldeh...
Abstract — Aims: The objective was to clarify the effect of alcohol dehydrogenase 2 (ADH2) and aldeh...
Background: Alcohol consumption has beneficial effects on mortality which are mainly due to reductio...
<p>OR, odds ratio; CI, confidence interval.</p><p>ORs were adjusted for age, usual ethanol consumpti...
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabolism and oxidativ...
Background. Previous population association studies have indicated that certain alleles of alcohol d...
genotype) modify ethanol metabolism and are prevalent (≈90% and ≈40%, respectively) in East Asians....
Background: Although beneficial associations have been reported between moderate alcohol intake and ...
Background: Although beneficial associations have been reported between moderate alcohol intake and ...
Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde dehydrogenase gene ALDH2...
[[abstract]]Background: Alcohol metabolism is one of the biological determinants that can influence ...
Aldehyde dehydrogenase with a low Michaelis constant (Kin), ALDH2, is a major enzyme in-volved in th...
Background: Alcohol consumption has beneficial effects on mortality which are mainly due to reductio...
Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde dehydrogenase gene ALDH2...
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabo-lism and oxidati...
Abstract — Aims: The objective was to clarify the effect of alcohol dehydrogenase 2 (ADH2) and aldeh...
Abstract — Aims: The objective was to clarify the effect of alcohol dehydrogenase 2 (ADH2) and aldeh...
Background: Alcohol consumption has beneficial effects on mortality which are mainly due to reductio...
<p>OR, odds ratio; CI, confidence interval.</p><p>ORs were adjusted for age, usual ethanol consumpti...
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabolism and oxidativ...
Background. Previous population association studies have indicated that certain alleles of alcohol d...