One of the major challenges of bone tissue engineering applications is to construct a fully vascularized implant that can adapt to hypoxic environments in vivo. The incorporation of proangiogenic factors into scaffolds is a widely accepted method of achieving this goal. Recently, the proangiogenic potential of mesenchymal stem cell-derived microvesicles (MSC-MVs) has been confirmed in several studies. In the present study, we incorporated MSC-MVs into alginate-polycaprolactone (PCL) constructs that had previously been developed for bone tissue engineering applications, with the aim of promoting angiogenesis and bone regeneration. MSC-MVs were first isolated from the supernatant of rat bone marrow-derived MSCs and characterized by scanning e...
Tissue engineering and regenerative medicine approaches use biomaterials in combination with cells t...
Biomaterials with excellent osteogenic and angiogenic activities are desirable to repair massive bon...
Regenerative engineering is a developing field that strongly relies on two strategies to promote the...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
A major limitation with current tissue-engineering approaches is creating functionally vascularized ...
In bone tissue engineering, vascularization is one of the critical factors that limit the effect of ...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
2013-04-07The need for hard tissues repair has increased in modern esthetic and reconstructive denti...
Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal. Previous s...
Tissue engineering and regenerative medicine approaches use biomaterials in combination with cells t...
Biomaterials with excellent osteogenic and angiogenic activities are desirable to repair massive bon...
Regenerative engineering is a developing field that strongly relies on two strategies to promote the...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
International audienceIn bone tissue engineering, autologous cells are combined with osteoconductive...
A major limitation with current tissue-engineering approaches is creating functionally vascularized ...
In bone tissue engineering, vascularization is one of the critical factors that limit the effect of ...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated t...
2013-04-07The need for hard tissues repair has increased in modern esthetic and reconstructive denti...
Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal. Previous s...
Tissue engineering and regenerative medicine approaches use biomaterials in combination with cells t...
Biomaterials with excellent osteogenic and angiogenic activities are desirable to repair massive bon...
Regenerative engineering is a developing field that strongly relies on two strategies to promote the...