Cytotoxic diterpenes from scoparia dulcis
- Ahsan, M.
- Islam, S.N.
- Gray, A.I.
- Stimson, W.H.
Publication date
July 2003
DOI Publisher
American Chemical Society (ACS) ISSN
0163-3864 Citation count (estimate)
21Abstract
Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines
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