Effects of gestational age at birth on cognitive performance: a function of cognitive workload demands.

OBJECTIVE: Cognitive deficits have been inconsistently described for late or moderately preterm children but are consistently found in very preterm children. This study investigates the association between cognitive workload demands of tasks and cognitive performance in relation to gestational age at birth. METHODS: Data were collected as part of a prospective geographically defined whole-population study of neonatal at-risk children in Southern Bavaria. At 8;5 years, n = 1326 children (gestation range: 23-41 weeks) were assessed with the K-ABC and a Mathematics Test. RESULTS: Cognitive scores of preterm children decreased as cognitive workload demands of tasks increased. The relationship between gestation and task workload was curvilinear and more pronounced the higher the cognitive workload: GA² (quadratic term) on low cognitive workload: R² = .02, p<0.001; moderate cognitive workload: R² = .09, p<0.001; and high cognitive workload tasks: R² = .14, p<0.001. Specifically, disproportionally lower scores were found for very (